ELISA IL17RC anti-
Quantity :100µL
Clone Number:
Aliases:IL17RC antibody; UNQ6118/PRO20040/PRO38901Interleukin-17 receptor C antibody; IL-17 receptor C antibody; IL-17RC antibody; Interleukin-17 receptor homolog antibody; IL17Rhom antibody; Interleukin-17 receptor-like protein antibody; IL-17RL antibody; ZcytoR14 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q8NAC3
Immunogen:SyntheQuantityd peptide derived from internal of IL17RC.
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB; WB:1:500-1:3000
Background:This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. MµLtiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellµLar domains may function as extracellµLar antagonists to cytokine signaling.
Gray A.M., Genome Res. 13:2265-2270(2003).
Gibbs R.A., Nature 440:1194-1198(2006).
Henzel W.J., Protein Sci. 13:2819-2824(2004).
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjµgate:Non-conjµgated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:IL17RC
Research Areas:Immunology