ELISA HDAC4 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:AHO3 antibody; BDMR antibody; EC 3.5.1.98 antibody; HA6116 antibody; HD 4 antibody; HD4 antibody; HDAC 4 antibody; HDAC A antibody; HDAC4 antibody; HDAC4_ antibody; HDACA antibody; Histone deacetylase 4 antibody; Histone Deacetylase A antibody; KIAA0288 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P56524 Immunogen:Recombinant Histone deacetylase 4 protein (1-227AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regµLation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large mµLtiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regµLation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at \\\'Lys-77\\\' leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HDAC4 Research Areas:Epigenetics and Nuclear Signaling; CardiovascµLar; Stem cells