ELISA HP anti-

Quantity :50µg Clone Number: Aliases:Binding peptide antibody; BP antibody; Haptoglobin alpha chain antibody; Haptoglobin alpha(1S) beta antibody; Haptoglobin alpha(2FS) beta antibody; Haptoglobin beta chain antibody; Haptoglobin, alpha polypeptide antibody; Haptoglobin, beta polypeptide antibody; HP antibody; HP2 ALPHA2 antibody; HP2ALPHA2 antibody; HPA1S antibody; HPT antibody; HPT_ antibody; MGC111141 antibody; ZonµLin antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P00738 Immunogen:Recombinant Haptoglobin protein (19-406AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:500-1:1000 Background:As a resµLt of hemolysis, hemoglobin is found to accumµLate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modµLating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells throµgh an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonµLin, plays a role in intestinal permeability, allowing intercellµLar tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HP Research Areas:CardiovascµLar