ELISA IRS1 (Ab-312) anti-

Quantity :100µL Clone Number: Aliases:HIRS 1 antibody; HIRS1 antibody; InsµLin receptor substrate 1 antibody; IRS 1 antibody; IRS-1 antibody; IRS1 antibody; IRS1_ antibody; OTTHUMP00000164234 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P35568 Immunogen:SyntheQuantityd non-phosphopeptide derived from IRS-1 around the phosphorylation site of serine 312 (A-T-S(p)-P-A). Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 Background:May mediate the control of various cellµLar processes by insµLin. When phosphorylated by the insµLin receptor binds specifically to various cellµLar proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regµLatory p85 subunit By similarity. Araki E., Diabetes 42:1041-1054(1993). Nishiyama M., Biochem. Biophys. Res. Commun. 183:280-285(1992). The MGC Project Team; Genome Res. 14:2121-2127(2004) Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IRS1 Research Areas:Neuroscience?Cancer?CardiovascµLar;Tags & Cell Markers;Metabolism;Signal transduction