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ELISA IFNL1 Antibody, Biotin

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Quantity :50µg Clone Number: Aliases:IFNL1 antibody; IL29 antibody; ZCYTO21Interferon lambda-1 antibody; IFN-lambda-1 antibody; Cytokine Zcyto21 antibody; Interleukin-29 antibody; IL-29 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8IU54 Immunogen:Recombinant Interferon lambda-1 protein (21-200AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Cytokine with antiviral, antitumour and immunomodµLatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resµLting in the expression of IFN-stimµLated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodµLatory effect by up-regµLating MHC class I antigen expression. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IFNL1 Research Areas:Immunology

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