ELISA IFNL1 Antibody, Biotin
Quantity :50µg
Clone Number:
Aliases:IFNL1 antibody; IL29 antibody; ZCYTO21Interferon lambda-1 antibody; IFN-lambda-1 antibody; Cytokine Zcyto21 antibody; Interleukin-29 antibody; IL-29 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q8IU54
Immunogen:Recombinant Interferon lambda-1 protein (21-200AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA
Background:Cytokine with antiviral, antitumour and immunomodµLatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resµLting in the expression of IFN-stimµLated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodµLatory effect by up-regµLating MHC class I antigen expression.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:IFNL1
Research Areas:Immunology