ELISA LOX anti-

Quantity :50µL Clone Number: Aliases:lox antibody; LYOX antibody; LYOX_ antibody; Lysyl oxidase antibody; MGC105112 antibody; Protein lysine 6 oxidase antibody; Protein-lysine 6-oxidase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P28300 Immunogen:Synthetic peptide of LOX Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:25-1:100 Background:The protein encoded by this gene is an extracellµLar copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellµLar matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LOX Research Areas:Cancer?CardiovascµLar;Signal transduction