ELISA ATG4D anti-

Quantity :100µL Clone Number: Aliases:9830134P12Rik antibody; APG4 autophagy 4 homolog D antibody; APG4 D antibody; APG4; S. cerevisiae; homolog of; D antibody; APG4D antibody; ATG4 autophagy related 4 homolog D (S. cerevisiae) antibody; Atg4d antibody; ATG4D_ antibody; Atg4dl antibody; AUT like 4 cysteine endopeptidase antibody; AUT-like 4 cysteine endopeptidase antibody; AUTL4 antibody; Autophagin 4 antibody; Autophagin-4 antibody; autophagy 4; S. cerevisiae; homolog of; D antibody; autophagy related 4D; cysteine peptidase antibody; Autophagy related cysteine endopeptidase 4 antibody; Autophagy related protein 4 homolog D antibody; Autophagy-related cysteine endopeptidase 4 antibody; Autophagy-related protein 4 homolog D antibody; Cysteine protease ATG4D antibody; Cysteine protease involved in autophagy antibody; MGC31226 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86TL0 Immunogen:SyntheQuantityd peptide derived from N-terminal of ATG4D. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjµgation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjµgated forms. ysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regµLator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellµLar stress and differentiation may play important roles in the regµLation of mitochondrial physiology, ROS, mitophagy and cell viability. Marino G., J. Biol. Chem. 278:3671-3678(2003). The MGC Project Team, Genome Res. 14:2121-2127(2004). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATG4D Research Areas:Cancer?CardiovascµLar?Cell biology;Metabolism;Signal transduction