ELISA ANO1 anti-

Quantity :50µL Clone Number: Aliases:ANO 1 antibody; ANO1 antibody; ANO1_ antibody; Anoctamin 1 antibody; Anoctamin 1 calcium activated chloride channel antibody; Anoctamin-1 antibody; Anoctamin1 antibody; Ca2+ activated Cl- channel antibody; Calcium Activated Chloride Channel antibody; Discovered on gastrointestinal stromal tumors protein 1 antibody; DOG 1 antibody; DOG1 antibody; FLJ10261 antibody; Membrane protein antibody; Oral cancer overexpressed 2 antibody; Oral cancer overexpressed protein 2 antibody; ORAOV 2 antibody; ORAOV2 antibody; TAOS 2 antibody; TAOS2 antibody; TMEM 16A antibody; TMEM16A antibody; Transmembrane protein 16A (eight membrane spanning domains) antibody; Transmembrane protein 16A antibody; Tumor amplified and overexpressed sequence 2 antibody; Tumor-amplified and overexpressed sequence 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q5XXA6 Immunogen:Synthetic peptide of ANO1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 Background:TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid mµLti-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. TMEM16A shares 90% sequence identity with its mouse counterpart, sµggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, sµggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ANO1 Research Areas:Tags & Cell Markers