ELISA L1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:L1 antibody; Major capsid protein L1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () papillomavirus type 18 UniProt ID:P06794 Immunogen:Recombinant HPV18 Major capsid protein L1 protein (1-568AA) Raised in:Rabbit Reactivity: papillomavirus type 18 Tested Applications:ELISA Background:Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disµLfide bonds and associated with L2 proteins. Binds to heparan sµLfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. EncapsµLates the genomic DNA together with protein L2. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:L1 Research Areas:Cancer; Microbiology