ELISA IRF2 anti-

Quantity :100µL Clone Number: Aliases:DKFZp686F0244 antibody; Interferon regµLatory factor 2 antibody; IRF 2 antibody; IRF-2 antibody; IRF2 antibody; IRF2_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P14316 Immunogen:SyntheQuantityd peptide derived from internal of IRF2. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100 Background:Specifically binds to the upstream regµLatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regµLation throµgh binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. Itoh S., Nucleic Acids Res. 17:8372-8372(1989). Cha Y., J. Biol. Chem. 269:5279-5287(1994). Staal A., J. Cell. Physiol. 185:269-279(2000). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IRF2 Research Areas:Epigenetics and Nuclear Signaling;Immunology