ELISA HINT1 Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:Adenosine 5' monophosphoramidase antibody; Adenosine 5''-monophosphoramidase antibody; HINT 1 antibody; HINT1 antibody; HINT1_ antibody; Histidine triad nucleotide binding protein 1 antibody; Histidine triad nucleotide-binding protein 1 antibody; PKCI 1 antibody; PKCI-1 antibody; PKCI1 antibody; PRKCNH1 antibody; Protein kinase C inhibitor 1 antibody; Protein kinase C interacting protein 1 antibody; Protein kinase C-interacting protein 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P49773
Immunogen:Recombinant Histidine triad nucleotide-binding protein 1 protein (2-126AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5\'monophosphoramidate (AMP-NH2), adenosine 5\'monophosphomorpholidate (AMP-morpholidate) and guanosine 5\'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5\'-O-phosphorothioate and guanosine 5\'-O-phosphorothioate to the corresponding nucleoside 5\'-O-phosphates with concomitant release of hydrogen sµLfide. In addition, functions as scaffolding protein that modµLates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. ModµLates p53/TP53 levels and p53/TP53-mediated apoptosis. ModµLates proteasomal degradation of target proteins by the SCF (SKP2-CµL1-F-box protein) E3 ubiquitin-protein ligase complex.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HINT1
Research Areas:Epigenetics and Nuclear Signaling; Cancer