ELISA LIMK1 anti-

Quantity :50µL Clone Number: Aliases:EC 2.7.11.1 antibody; LIM domain kinase 1 antibody; LIM motif-containing protein kinase antibody; LIMK antibody; LIMK-1 antibody; limk1 antibody; LIMK1_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P53667 Immunogen:Synthetic peptide of LIMK1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Althoµgh zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regµLates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellµLar processes associated with cytoskeletal structure. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LIMK1 Research Areas:Neuroscience;Signal transduction