ELISA ARPC2 Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:Actin related protein 2/3 complex subunit 2 34kDa antibody; Actin related protein 2/3 complex subunit 2 antibody; Actin-related protein 2/3 complex subunit 2 antibody; ARC 34 antibody; ARC34 antibody; Arp2/3 complex 34 kDa subunit antibody; ARP2/3 protein compex subunit 34 antibody; ARPC 2 antibody; Arpc2 antibody; ARPC2_ antibody; p34 Arc antibody; p34-ARC antibody; p34Arc antibody; PNAS 139 antibody; PNAS139 antibody; PRO 2446 antibody; PRO2446 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:O15144
Immunogen:Recombinant Actin-related protein 2/3 complex subunit 2 protein (1-250AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:Actin-binding component of the Arp2/3 complex, a mµLtiprotein complex that mediates actin polymerization upon stimµLation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regµLating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ARPC2
Research Areas:Signal transduction