ELISA LAMTOR3 anti-

Quantity :50µL Clone Number: Aliases:LAMTOR3 antibody; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 antibody; LTOR3_ antibody; MAP2K1IP1 antibody; MEK binding partner 1 antibody; MEK partner 1 antibody; MEK-binding partner 1 antibody; Mitogen activated protein kinase kinase 1 interacting protein 1 antibody; Mitogen-activated protein kinase kinase 1-interacting protein 1 antibody; Mitogen-activated protein kinase scaffold protein 1 antibody; Mp1 antibody; RagµLator complex protein LAMTOR3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UHA4 Immunogen:Recombinant RagµLator complex protein LAMTOR3 protein (1-124AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:As part of the RagµLator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids throµgh a mechanism involving the lysosomal V-ATPase, the RagµLator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated RagµLator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LAMTOR3 Research Areas:Signal transduction