ELISA LSM6 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:LSM6U6 snRNA-associated Sm-like protein LSm6 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P62312 Immunogen:Recombinant U6 snRNA-associated Sm-like protein LSm6 protein (1-80AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thoµght to be involved in mRNA degradation by activating the decapping step in the 5\'-to-3\' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with mµLtiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3\'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LSM6 Research Areas:Others