ELISA LRPPRC Antibody, HRP

Quantity :50µg Clone Number: Aliases:130 kDa leucine-rich protein antibody; gp130 antibody; Leucine-rich PPR motif-containing protein antibody; Leucine-rich PPR-motif containing protein antibody; LPPRC_ antibody; LRP 130 antibody; lrpprc antibody; mitochondrial antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P42704 Immunogen:Recombinant Leucine-rich PPR motif-containing protein, mitochondrial protein (901-1036AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regµLation. Cooperates with PPARGC1A to regµLate certain mitochondrially encoded genes and gluconeogenic genes and may regµLate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regµLation of the mµLtidrµg-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LRPPRC Research Areas:Epigenetics and Nuclear Signaling; Neuroscience