ELISA LGMN anti-

Quantity :50µg Clone Number: Aliases:AEP antibody; Asparaginyl endopeptidase antibody; cysteine 1 antibody; Cysteine protease 1 antibody; EC 3.4.22.34 antibody; Legumain antibody; LGMN antibody; LGMN_ antibody; LGMN1 antibody; Protease antibody; Protease cysteine 1 (legumain) antibody; Protease cysteine 1 antibody; PRSC1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q99538 Immunogen:Recombinant Legumain protein (199-312AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:500-1:1000 Background:Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubµLes. Required for normal degradation of internalized EGFR. Plays a role in the regµLation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LGMN Research Areas:Cancer; Cell biology; Immunology; Metabolism; Signal transduction