ELISA LAT anti-

Quantity :50µL Clone Number: Aliases:36 kDa phospho tyrosine adapter protein antibody; 36 kDa phospho-tyrosine adapter protein antibody; 36 kDa phospho-tyrosine adaptor protein antibody; LAT 1 antibody; lat antibody; LAT_ antibody; LAT1 antibody; Linker for activation of T cells antibody; Linker for activation of T cells family member 1 antibody; linker for activation of T cells; transmembrane adaptor antibody; Linker for activation of T-cells family member 1 antibody; p36 38 antibody; p36-38 antibody; pp36 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43561 Immunogen:Recombinant Linker for activation of T-cells family member 1 protein (28-233AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobµLin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobµLin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellµLar events such as mobilization of intracellµLar calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization throµgh the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecµLes. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:LAT Research Areas:Immunology; Signal transduction