ELISA Keap1 anti-

Quantity :50µg Clone Number: Aliases:Keap1 antibody; Inrf2 antibody; Kiaa0132Kelch-like ECH-associated protein 1 antibody; Cytosolic inhibitor of Nrf2 antibody; INrf2 antibody Product Type:Polyclonal Antibody Immunogen Species:Mus muscµLus (Mouse) UniProt ID:Q9Z2X8 Immunogen:Recombinant Mouse Kelch-like ECH-associated protein 1 protein (1-624AA) Raised in:Rabbit Reactivity:Mouse, Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000 Background:Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CµL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resµLting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Keap1 Research Areas:Others