ELISA ITGB7 anti-

Quantity :50µL Clone Number: Aliases:Gut homing receptor beta subunit antibody; Integrin beta 7 subunit antibody; Integrin beta-7 antibody; Integrin beta-P antibody; Integrin; beta 7 antibody; ITB7 antibody; ITB7_ antibody; Itgb7 antibody; Ly69 antibody; M290 IEL antigen antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P26010 Immunogen:Recombinant Integrin beta-7 protein (1-140AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecµLe that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecµLes MADCAM1 which is normally expressed by the vascµLar endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellµLar matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thoµght to be the major trigger of AIDS disease. Interaction woµLd involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HmL-1) is a receptor for E-cadherin. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ITGB7 Research Areas:Signal transduction; Stem cells