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ELISA ITGB4 Antibody, HRP

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Quantity :50µg Clone Number: Aliases:CD 104 antibody; CD104 antibody; CD104 antigen antibody; gp150 antibody; Integrin beta 4 subunit antibody; Integrin beta-4 antibody; ITB4_ antibody; ITG B4 antibody; ITGB 4 antibody; Itgb4 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P16144 Immunogen:Recombinant Integrin beta-4 protein (1401-1533AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regµLation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ITGB4 Research Areas:Signal transduction

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