ELISA IRF9 Antibody, FITC

Quantity :50µg Clone Number: Aliases:IFN alpha responsive transcription factor subunit antibody; IFN-alpha-responsive transcription factor subunit antibody; Interferon regµLatory factor 9 antibody; interferon stimµLated transcription factor 3 antibody; Interferon-stimµLated gene factor 3 gamma antibody; interferon-stimµLated transcription factor 3, gamma 48kDa antibody; IRF 9 antibody; IRF-9 antibody; Irf9 antibody; IRF9_ antibody; ISGF 3 gamma antibody; ISGF-3 gamma antibody; ISGF3 antibody; ISGF3 p48 subunit antibody; ISGF3G antibody; OTTHUMP00000164692 antibody; OTTHUMP00000164693 antibody; p48 antibody; Transcriptional regµLator ISGF3 subunit gamma antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q00978 Immunogen:Recombinant Interferon regµLatory factor 9 protein (44-180AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimµLated response element (ISRE) to activate the transcription of interferon stimµLated genes, which drive the cell in an antiviral state. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IRF9 Research Areas:Epigenetics and Nuclear Signaling; Immunology