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ELISA IL12B Antibody, Biotin

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Quantity :50µg Clone Number: Aliases:IL12B antibody; Interleukin-12 subunit beta antibody; IL-12B antibody; Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody; CLMF p40 antibody; IL-12 subunit p40 antibody Product Type:Polyclonal Antibody Immunogen Species:Ovis aries (Sheep) UniProt ID:P68220 Immunogen:Recombinant Sheep Interleukin-12 subunit beta protein (23-327AA) Raised in:Rabbit Reactivity:Sheep Tested Applications:ELISA Background:Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimµLate the production of IFN-gamma by resting PBMC By similarity.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimµLates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis By similarity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IL12B Research Areas:Immunology

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