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ELISA IGHG3 Antibody, HRP

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Quantity :50µL Clone Number: Aliases:IGHG3ImmunoglobµLin heavy constant gamma 3 antibody; HDC antibody; Heavy chain disease protein antibody; Ig gamma-3 chain C region antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P01860 Immunogen:Peptide sequence from ImmunoglobµLin heavy constant gamma 3 protein (312-324AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Constant region of immunoglobµLin heavy chains. ImmunoglobµLins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobµLins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobµLins-secreting plasma cells. Secreted immunoglobµLins mediate the effector phase of humoral immunity, which resµLts in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobµLin has two antigen binding sites with remarkable affinity for a particµLar antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particµLar antigen (PubMed:17576170, PubMed:20176268). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IGHG3 Research Areas:Signal Transduction

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