ELISA IFIT1 Antibody, Biotin
Quantity :50µg
Clone Number:
Aliases:C56 antibody; G10P1 antibody; GARG 16 antibody; GARG16 antibody; IFI 56 antibody; IFI 56K antibody; IFI-56K antibody; IFI56 antibody; IFIT-1 antibody; Ifit1 antibody; IFIT1_ antibody; IFNAI1 antibody; Interferon alpha inducible protein (MW 56kD) antibody; Interferon induced 56 kDa protein antibody; Interferon induced protein 56 antibody; Interferon inducible mRNA 561 antibody; Interferon-induced 56 kDa protein antibody; Interferon-induced protein with tetratricopeptide repeats 1 antibody; ISG56 antibody; OTTHUMP00000020062 antibody; P56 antibody; RNM561 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P09914
Immunogen:Recombinant Interferon-induced protein with tetratricopeptide repeats 1 protein (1-181AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA
Background:Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5\'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2\'-O-methylation of the 5\' cap and bear a 5\'-triphosphate group instead, are specific from viruses, providing a molecµLar signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2\'-O-methylase for their mRNAs or by stealing host cap containing the 2\'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including papilloma and hepatitis C viruses.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:IFIT1
Research Areas:Immunology