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ELISA IFIT1 Antibody, Biotin

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Quantity :50µg Clone Number: Aliases:C56 antibody; G10P1 antibody; GARG 16 antibody; GARG16 antibody; IFI 56 antibody; IFI 56K antibody; IFI-56K antibody; IFI56 antibody; IFIT-1 antibody; Ifit1 antibody; IFIT1_ antibody; IFNAI1 antibody; Interferon alpha inducible protein (MW 56kD) antibody; Interferon induced 56 kDa protein antibody; Interferon induced protein 56 antibody; Interferon inducible mRNA 561 antibody; Interferon-induced 56 kDa protein antibody; Interferon-induced protein with tetratricopeptide repeats 1 antibody; ISG56 antibody; OTTHUMP00000020062 antibody; P56 antibody; RNM561 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P09914 Immunogen:Recombinant Interferon-induced protein with tetratricopeptide repeats 1 protein (1-181AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5\'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2\'-O-methylation of the 5\' cap and bear a 5\'-triphosphate group instead, are specific from viruses, providing a molecµLar signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2\'-O-methylase for their mRNAs or by stealing host cap containing the 2\'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including papilloma and hepatitis C viruses. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:IFIT1 Research Areas:Immunology

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