ELISA IER3 anti-
Quantity :50µg
Clone Number:
Aliases:DIF2 antibody; Differentiation-dependent gene 2 protein antibody; GLY96 antibody; IER3 antibody; IEX1_ antibody; IEX1L antibody; Immediate early protein GLY96 antibody; Immediate early response 3 antibody; Immediate early response 3 protein antibody; Immediately early gene X 1 antibody; PACAP-responsive gene 1 protein antibody; PRG 1 antibody; PRG1 antibody; Protein DIF 2 antibody; Protein DIF-2 antibody; Protein PRG1 antibody; Radiation-inducible immediate-early gene IEX-1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P46695
Immunogen:Recombinant Radiation-inducible immediate-early gene IEX-1 protein (1-82AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200
Background:May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:IER3
Research Areas:Cancer; Cell biology; Stem cells