ELISA HMGB3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:chromosomal protein; Nonhistone; HMG4 antibody; High mobility group (nonhistone chromosomal) protein 4 antibody; High mobility group box 3 antibody; High mobility group protein 2a antibody; High mobility group protein 4 antibody; High mobility group protein B3 antibody; High mobility group protein HMG4 antibody; HMG 4 antibody; HMG-2a antibody; HMG-4 antibody; HMG2A antibody; HMGB 3 antibody; Hmgb3 antibody; HMGB3_ antibody; MGC90319 antibody; Non histone chromosomal protein antibody; Nonhistone chromosomal protein HMG4 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15347 Immunogen:Recombinant High mobility group protein B3 protein (1-103AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:MµLtifunctional protein with various roles in different cellµLar compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regµLates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regµLate the balance between self-renewal and differentiation. Involved in negative regµLation of canonical Wnt signaling (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HMGB3 Research Areas:Epigenetics and Nuclear Signaling