ELISA HAMP anti-

Quantity :100µL Clone Number: Aliases:Hamp antibody; HEPC antibody; HEPC_ antibody; Hepc20 antibody; Hepc25 antibody; HEPCIDIN antibody; Hepcidin 20 antibody; Hepcidin 25 antibody; Hepcidin antimicrobial peptide antibody; Hepcidin-20 antibody; Hepcidin25 antibody; HFE2 antibody; HFE2B antibody; LEAP 1 antibody; LEAP-1 antibody; LEAP1 antibody; Liver expressed antimicrobial peptide antibody; Liver-expressed antimicrobial peptide 1 antibody; PLTR antibody; Putative liver tumor regressor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P81172 Immunogen:Recombinant protein of HAMP Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; WB:1:500-1:2000, IHC:1:50-1:200 Background:The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regµLation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecµLar bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that resµLts in cardiomyopathy, cirrhosis, and endocrine failure. Clonality:Polyclonal Isotype:IgG Purification Method:Affinity purification Conjµgate:Non-conjµgated Buffer:Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HAMP Research Areas:Cancer?CardiovascµLar;Metabolism;Signal transduction