ELISA GZMA anti-
Quantity :50µL
Clone Number:
Aliases:CTL tryptase antibody; CTLA3 antibody; Cytolytic t cell and natural killer cell specific trypsin like serine protease antibody; Cytotoxic T lymphocyte associated serine esterase 3 antibody; Cytotoxic T lymphocyte proteinase 1 antibody; Cytotoxic T-lymphocyte proteinase 1 antibody; Fragmentin 1 antibody; Fragmentin-1 antibody; GRAA_ antibody; Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3 antibody; Granzyme A (Cytotoxic T lymphocyte associated serine esterase 3, Hanukah factor serine protease) antibody; Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3) antibody; Granzyme A antibody; Granzyme A precursor antibody; Granzyme-1 antibody; GZMA antibody; H factor antibody; Hanukah factor serine protease antibody; Hanukkah factor antibody; HF antibody; HFSP antibody; TSP1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P12544
Immunogen:Recombinant Granzyme A protein (29-262AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Abundant protease in the cytosolic granµLes of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell throµgh the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after \\\'Lys-31\\\' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after \\\'Lys-189\\\', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:Non-conjµgated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GZMA
Research Areas:Cell biology; Immunology