ELISA GPR75 Antibody, HRP

Quantity :50µg Clone Number: Aliases:G protein coupled receptor 75 antibody; GPR chr2 antibody; Gpr75 antibody; GPR75_ antibody; GPRchr2 antibody; OTTHUMP00000159608 antibody; Probable G protein coupled receptor 75 antibody; Probable G-protein coupled receptor 75 antibody; WI 31133 antibody; WI31133 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O95800 Immunogen:Recombinant Probable G-protein coupled receptor 75 protein (372-540AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimµLates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival throµgh activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regµLate insµLin secretion by pancreatic islet cells throµgh activation of this receptor. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GPR75 Research Areas:Signal transduction