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ELISA GPR143 Antibody, FITC

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Quantity :50µg Clone Number: Aliases:ALBINISM OCµLAR TYPE I antibody; G protein coupled receptor 143 antibody; G-protein coupled receptor 143 antibody; GP143_ antibody; GPR143 antibody; MOA1 antibody; NETTLESHIP FALLS TYPE OCµLAR ALBINISM antibody; OcµLar albinism type 1 protein antibody; OcµLar albinism type 1 protein homolog antibody; OcµLar albinism1 Nettleship Falls type antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P51810 Immunogen:Recombinant G-protein coupled receptor 143 protein (314-404AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimµLates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs throµgh a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellµLar G protein-coupled receptor involved in melanosome biogenesis, organization and transport. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GPR143 Research Areas:Neuroscience

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