ELISA GPC1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:FLJ38078 antibody; glypican antibody; Glypican proteoglycan 1 antibody; glypican1 antibody; GPC 1 antibody; Gpc1 antibody; GPC1_ antibody; Secreted glypican-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P35052 Immunogen:Recombinant Glypican-1 protein (342-530AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Cell surface proteoglycan that bears heparan sµLfate. Binds, via the heparan sµLfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sµLfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GPC1 Research Areas:Neuroscience; Cancer; Signal transduction