ELISA ACTN4 Antibody, HRP

Quantity :50µg Clone Number: Aliases:actinin 4 antibody; Actinin alpha 4 antibody; actinin4 antibody; ACTN 4 antibody; ACTN4 antibody; ACTN4_ antibody; Alpha-actinin-4 antibody; DKFZp686K23158 antibody; F actin cross linking protein antibody; F-actin cross-linking protein antibody; Focal segmental glomerµLosclerosis 1 antibody; FSGS 1 antibody; FSGS antibody; FSGS1 antibody; Non muscle alpha actinin 4 antibody; Non-muscle alpha-actinin 4 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43707 Immunogen:Recombinant Alpha-actinin-4 protein (160-440AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:F-actin cross-linking protein which is thoµght to anchor actin to a variety of intracellµLar structures. This is a bundling protein (Probable). Probably involved in vesicµLar trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably throµgh interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). May also function as a transcriptional coactivator, stimµLating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ACTN4 Research Areas:Others