ELISA ASAH2 anti-
Quantity :50µg
Clone Number:
Aliases:Acylsphingosine deacylase 2 antibody; AI585898 antibody; ASAH2 antibody; ASAH2_ antibody; BCDase antibody; hCD antibody; HNAC1 antibody; LCDase antibody; MGC129777 antibody; mitochondrial ceramidase antibody; N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2 antibody; N acylsphingosine amidohydrolase 2 antibody; N CDase antibody; N-acylsphingosine amidohydrolase 2 antibody; N-CDase antibody; NCDase antibody; Neutral ceramidase soluble form antibody; Non lysosomal ceramidase antibody; Non-lysosomal ceramidase antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9NR71
Immunogen:Recombinant Neutral ceramidase protein (255-506AA)
Raised in:Rabbit
Reactivity:, Rat
Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:500
Background:Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regµLator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regµLating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ASAH2
Research Areas:Others