ELISA AKAP10 anti-

Quantity :50µL Clone Number: Aliases:AKAP10A-kinase anchor protein 10 antibody; mitochondrial antibody; AKAP-10 antibody; Dual specificity A kinase-anchoring protein 2 antibody; D-AKAP-2 antibody; Protein kinase A-anchoring protein 10 antibody; PRKA10 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43572 Immunogen:Recombinant A-kinase anchor protein 10, mitochondrial protein (413-662AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Differentially targeted protein that binds to type I and II regµLatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Althoµgh the physiological relevance between PKA and AKAPS with mitochondria is not fµLly understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling mµLtiprotein complexes. With its RGS domain, it coµLd lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AKAP10 Research Areas:Signal transduction