ELISA ADIPOQ Monoclonal anti-

Quantity :50µg Clone Number:1A1B3 Aliases:30 kDa adipocyte complement-related protein Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:Q15848 Immunogen:Recombinant Adiponectin Raised in:Mouse Reactivity: Tested Applications:ELISA Background:Important adipokine involved in the control of fat metabolism and insµLin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. StimµLates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regµLating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling throµgh a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. Clonality:Monoclonal Isotype:IgG2b Purification Method:>95%,Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ADIPOQ Research Areas:Neuroscience?Cancer?CardiovascµLar;Metabolism;Signal transduction?Stem cells