7-Hydroxyflavone (Standard) [6665-86-7]

7-Hydroxyflavone (Standard) [6665-86-7] : Size : 1L - Certification : Research Use Only - 7-Hydroxyflavone (Standard) is the analytical standard of 7-Hydroxyflavone. This product is intended for research and analytical applications. 7-Hydroxyflavone is a flavonoid isolated from Clerodendrum phlomidis, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. 7-Hydroxyflavone inhibits PKM2 with an IC50 of 2.12 microM. 7-Hydroxyflavone inhibits COX-2 and 5-LOX with IC50 of 27 microg/mL and 33 microg/mL. 7-Hydroxyflavone is orally active[1][2][4]. -