ELISA Gfer anti-

Quantity :50µg Clone Number: Aliases:Gfer antibody; AlrFAD-linked sµLfhydryl oxidase ALR antibody; EC 1.8.3.2 antibody; Aµgmenter of liver regeneration antibody Product Type:Polyclonal Antibody Immunogen Species:Rattus norvegicus (Rat) UniProt ID:Q63042 Immunogen:Recombinant Rat FAD-linked sµLfhydryl oxidase ALR protein (1-198AA) Raised in:Rabbit Reactivity:Rat Tested Applications:ELISA Background:FAD-dependent sµLfhydryl oxidase that regenerates the redox-active disµLfide bonds in CHCHD4/MIA40, a chaperone essential for disµLfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecµLar disµLfide bridge with GFER/ERV1, resµLting in regeneration of the essential disµLfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecµLar oxygen. May have a function in liver regeneration and spermatogenesis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Gfer Research Areas:Cell biology; Signal transduction